Why do I have a large bump on my arm where my allergy injection was given?

A large local reaction does not mean a patient is having a systemic reaction. It can be comforted with ice, ibuprofen, acetaminophen or Benadryl and should be reported to the nurse the next time you are in for an injection. It does not require further treatment and it is not necessary to call the on call Doctor after hours to be reported.